The geometry of the device is considered all-important
and is epitomised by the high-tech precise fit of uncemented
CAD-CAM femoral hip stems. During the late 1980s a unique
Hip Design Workstation was developed by Professor Walker
at the Centre for Biomedical Engineering. By digitising
key anatomical landmarks on a pair of bi-planar radiographs
the 3 dimensional shape of the proximal femoral canal can
be generated. Using this 3D mesh of the internal surface
of the femoral cortex, the optimal femoral stem design is
calculated. Manipulation of the software enables the designer
to correct the design for retro or anteversion of the femoral
neck. Additional design features can be incorporated and
can be selected from a menu of choices including anti-rotation
cutting flutes, and the presence, the size and position
of a collar. On completion of the on-screen design, automated
software produces the machining code for the computer controlled
milling machines that are capable of producing patient specific
femoral hip stems within one hour with extreme precision.
Over 2,100 femoral hip stems produced for both primary
and revision joint replacement have in general been for
indications such as CDH, JRA and the more severe failed
standard hip arthroplasties. Concurrent mathematical modelling
studies using finite element analysis combined with dual
energy x-ray absorptiometry (DEXA) and migration studies
have shown that optimising the fit and fill of the proximal
femoral canal by incorporating a lateral flare permits more
natural physiological loading and preferential adaptive
bone remodelling and osseointegration. The migration studies
showed that after 24 months the amount of axial sinkage
for both the primary and revision custom was less than that
of the gold standard of cemented Charnley and Stanmore replacements
(Walker, 2000). Furthermore, the DEXA studies of the revision
patients identified that after 4 years bone density was
maintained within 12% of the immediate postoperative values.